Associations Between Severe Obesity and Depression: Results From the National Health and Nutrition Examination Survey, 2005-2006
2011

Obesity and Depression in Women

Sample size: 3599 publication Evidence: moderate

Author Information

Author(s): Keddie Arlene M.

Primary Institution: Northern Illinois University

Hypothesis

Is there an association between obesity and depression in women, and do sex and severity of obesity modify this association?

Conclusion

The study found an association between severe obesity and depression in women, particularly those with class III obesity.

Supporting Evidence

  • Women with a large waist circumference had almost double the prevalence of depression compared to those with a small waist circumference.
  • Women with a BMI of 40 kg/m2 or more had more than 4 times the odds of being depressed compared to women with a normal weight.
  • Adjustment for demographic factors reduced the odds of depression in women with class III obesity compared to normal weight women.

Takeaway

This study shows that women who are very obese are more likely to feel depressed. It suggests that being very overweight can affect how you feel.

Methodology

The study used logistic regression models to analyze data from the National Health and Nutrition Examination Survey, focusing on nonpregnant adults aged 20 and older.

Potential Biases

Selection bias may have occurred due to the exclusion of participants with missing data.

Limitations

The study's cross-sectional design limits the ability to determine causality, and there was low statistical power for detecting significant associations in men due to the rarity of depression.

Participant Demographics

The sample included 3,599 nonpregnant adults aged 20 years or older, with a higher proportion of women being older, less educated, and having more chronic conditions.

Statistical Information

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.5888/pcd8.100151

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