The role of diet in the development of breast cancer: a case-control study of patients with breast cancer, benign epithelial hyperplasia and fibrocystic disease of the breast
1991

Diet and Breast Cancer: A Case-Control Study

Sample size: 514 publication Evidence: moderate

Author Information

Author(s): D.M. Ingram, E. Nottage, T. Roberts

Primary Institution: Queen Elizabeth II Medical Centre

Hypothesis

Does diet play a role in the development of breast cancer?

Conclusion

The study suggests that certain dietary patterns may influence the risk of developing breast cancer.

Supporting Evidence

  • Consumption of red meat and savory meals is associated with increased breast cancer risk.
  • Women with breast cancer were less likely to change their diet compared to controls.
  • Fruit consumption appears to have a protective effect against breast cancer.

Takeaway

Eating more chicken, fish, fruits, and vegetables might help lower the risk of breast cancer, while eating red meat and savory meals could be harmful.

Methodology

A case-control study involving structured interviews and dietary questionnaires was conducted among women with breast cancer and benign breast diseases.

Potential Biases

Potential bias due to self-reported dietary changes and the timing of dietary assessments relative to diagnosis.

Limitations

The study may not account for dietary changes made after diagnosis, and the influence of nutrition on breast cancer may take years to manifest.

Participant Demographics

Women aged 19-86, including breast cancer patients, benign epithelial hyperplasia patients, fibrocystic disease patients, and controls.

Statistical Information

P-Value

p<0.05

Confidence Interval

0.1-0.9

Statistical Significance

p<0.05

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