Bgee in 2024: Updates on Gene Expression Data and Tools
Author Information
Author(s): Bastian Frederic, Cammarata Alessandro, Carsanaro Sara, Detering Harald, Huang Wan-Ting, Joye Sagane, Niknejad Anne, Nyamari Marion, Mendes de Farias Tarcisio, Moretti Sébastien, Tzivanopoulou Marianna, Wollbrett Julien, Robinson-Rechavi Marc
Primary Institution: SIB Swiss Institute of Bioinformatics
Conclusion
Bgee has successfully integrated single-cell RNA-sequencing data and improved its tools for accessing and analyzing gene expression data across multiple species.
Supporting Evidence
- Bgee now includes 52 species, up from 29, enhancing its utility for comparative studies.
- The new web interface allows users to easily access and query gene expression data.
- Bgee focuses on integrating only healthy wild-type data for clear gene expression patterns.
- Single-cell RNA-sequencing data have been curated to improve data reproducibility and integration.
- Bgee has been recognized as a Global Core Biodata Resource.
Takeaway
Bgee is like a big library where scientists can find and compare how genes work in different animals, and now it has even more information about tiny cells.
Methodology
Bgee integrates gene expression data from various species, focusing on single-cell RNA-sequencing, and provides tools for standardized data access and analysis.
Limitations
The integration of diverse datasets can lead to challenges in standardization and comparison due to varying nomenclature and definitions of cell types.
Digital Object Identifier (DOI)
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