Sensitivity to heat in MS patients: a factor strongly influencing symptomology - an explorative survey
2011

Heat Sensitivity in MS Patients

Sample size: 256 publication 10 minutes Evidence: moderate

Author Information

Author(s): Flensner Gullvi, Ek Anna-Christina, Söderhamn Olle, Landtblom Anne-Marie

Primary Institution: Linköping University

Hypothesis

The study aims to investigate the occurrence of heat sensitivity and its relations to disease course, disability, common MS-related symptoms, and ongoing immunosuppressive treatments among individuals diagnosed with MS.

Conclusion

Heat sensitivity in MS patients is a key symptom that is highly correlated with disabling symptoms such as fatigue, pain, concentration difficulty, and urination urgency.

Supporting Evidence

  • 58% of responding patients reported heat sensitivity.
  • Heat sensitivity was significantly related to fatigue, pain, concentration difficulties, and urination urgency.
  • 70% of heat-sensitive participants preferred a room temperature of less than 20°C.

Takeaway

People with multiple sclerosis often feel worse when they get hot, which can make them feel more tired and have other problems.

Methodology

A cross-sectional survey was conducted with a questionnaire sent to MS patients aged 20-65 with an EDSS score of 0-6.5.

Potential Biases

Potential bias due to self-reported data and the specific demographic of participants.

Limitations

The study may have a selection bias towards patients with relapsing-remitting MS and those receiving treatment.

Participant Demographics

The participants included 195 women (76%) and 61 men (24%), aged 20-65, with a majority having relapsing-remitting MS.

Statistical Information

P-Value

p<0.001

Confidence Interval

95%CI = 1.02-1.08

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/1471-2377-11-27

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