(4-Methylphenylsulfonyl)4,7,13,16-tetraoxa-1,10,21-triazabicyclo[8.8.5]tricosane-19,23-dione: an N-tosylated macrobicyclic dilactam
2011
Study of a Macrobicyclic Compound
publication
Evidence: moderate
Author Information
Author(s): Ellis Trevor K., Clayton Stephen M. J., Powell Douglas R., Taylor Richard W.
Primary Institution: University of Oklahoma, Department of Chemistry and Biochemistry
Conclusion
The study presents the crystal structure of a new macrobicyclic compound with specific donor atom arrangements.
Supporting Evidence
- The compound contains two tertiary amide bridgehead N atoms.
- It has a central cavity defined by an 18-membered ring and two 15-membered rings.
- The toluenesulfonamide N atom adopts an exo orientation with respect to the central cavity.
Takeaway
The researchers looked at a special molecule that has a unique shape and can hold onto certain metal ions.
Methodology
The compound was synthesized through high-dilution condensation and purified using flash column chromatography.
Digital Object Identifier (DOI)
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