MRSA Acquisition After Liver Transplantation
Author Information
Author(s): Hashimoto Masao, Sugawara Yasuhiko, Tamura Sumihito, Kaneko Junichi, Matsui Yuichi, Togashi Junichi, Moriya Kyoji, Koike Kazuhiko, Makuuchi Masatoshi
Primary Institution: University of Tokyo
Hypothesis
What are the incidence and risk factors for acquiring MRSA after living donor liver transplantation?
Conclusion
MRSA arose early after LDLT in adults with a high incidence, indicating the need for periodic surveillance cultures.
Supporting Evidence
- Postoperative MRSA acquisition was detected in 35 of 158 patients by median postoperative day 18.
- Age (>= 60 y) and perioperative dialysis predicted MRSA acquisition.
- Postoperative use of fluoroquinolone was negatively associated with MRSA acquisition.
Takeaway
After liver transplants, some patients can get a germ called MRSA, which can make them sick. It's important to check for this germ regularly.
Methodology
The study reviewed medical records of 158 patients who underwent LDLT and analyzed risk factors for MRSA acquisition using multivariate analysis.
Potential Biases
Potential bias due to the retrospective nature of the study and the exclusion of preoperatively colonized patients.
Limitations
The study did not analyze MRSA carriage patterns or differentiate specific MRSA strains.
Participant Demographics
Median age of participants was 51 years, with a range from 19 to 67 years.
Statistical Information
P-Value
0.01
Confidence Interval
3.33 (1.17–9.58)
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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