Intraosseous Basivertebral Nerve Ablation: 5-Year Outcomes
Author Information
Author(s): Khalil Jad G., Truumees Eeric, Macadaeg Kevin, Nguyen Daniel T.D., Moore Gregory A., Lukes Dylan, Fischgrund Jeffrey
Primary Institution: Beaumont University Hospital
Hypothesis
What are the long-term outcomes of intraosseous basivertebral nerve ablation for chronic low back pain?
Conclusion
Intraosseous basivertebral nerve ablation significantly improved pain and function scores over five years, with a strong safety profile and reduced healthcare utilization.
Supporting Evidence
- 249 participants completed a five-year follow-up with significant improvements in pain and function.
- 65.2% of participants who were taking opioids at baseline were no longer taking them at five years.
- 32.1% of patients reported being pain-free at five years.
- Significant reductions in healthcare utilization for the same pain source were observed.
Takeaway
This study shows that a treatment for back pain can help people feel better and do more activities for a long time, without serious side effects.
Methodology
The study pooled results from three clinical trials analyzing pain and function improvements at five years post-treatment using paired t-tests.
Potential Biases
Potential bias due to industry sponsorship and open-label design.
Limitations
The study design was open-label and industry-sponsored, with a lack of long-term comparator groups.
Participant Demographics
Mean age was 48.5 years, 47.8% female, and 71.9% had back pain for ≥5 years.
Statistical Information
P-Value
p<0.0001
Confidence Interval
95% CI 25.83, 30.19 for ODI; 95% CI 4.01, 4.63 for NPS
Statistical Significance
p<0.0001
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website