Phylogeny of European Bat Lyssavirus 1 in Eptesicus isabellinus Bats, Spain
2011

Phylogeny of European Bat Lyssavirus 1 in Eptesicus isabellinus Bats, Spain

Sample size: 12 publication Evidence: moderate

Author Information

Author(s): Sonia Vázquez-Morón, Javier Juste, Carlos Ibáñez, José M. Berciano, Juan E. Echevarría

Primary Institution: Instituto de Salud Carlos III

Hypothesis

To better understand the epidemiology of European bat lyssavirus 1 (EBLV-1) in Europe, we phylogenetically characterized Lyssavirus from Eptesicus isabellinus bats in Spain.

Conclusion

The study found that EBLV-1 strains from Spain do not belong to subtype 1b and have a different evolutionary history compared to other strains.

Supporting Evidence

  • EBLV-1 in other bat species has rarely been described.
  • 10 cases of human exposure after contact with infected bats have been reported.
  • Phylogenetic analyses formed a monophyletic cluster of the EBLV-1 strains from Spain.

Takeaway

Scientists studied a virus in bats from Spain to see how it spreads and found that it has a unique history compared to similar viruses in other countries.

Methodology

The study sequenced bat brains positive for Lyssavirus antigen and performed phylogenetic analyses using various statistical methods.

Limitations

The study's findings may not be generalizable to all bat populations in Europe due to the specific focus on E. isabellinus bats in Spain.

Participant Demographics

The study focused on Eptesicus isabellinus bats in southern Spain.

Digital Object Identifier (DOI)

10.3201/eid1703100894

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