Effects of Exercise Training on Patients with Pulmonary Arterial Hypertension
Author Information
Author(s): Louise Ganderton, Sue Jenkins, Kevin Gain, Robin Fowler, Peta Winship, Dianne Lunt, Eli Gabbay
Primary Institution: Curtin University
Hypothesis
A 12 week individualised, whole body exercise training program will improve exercise capacity and health-related quality of life in patients with pulmonary arterial hypertension.
Conclusion
The study aims to determine if exercise training is safe and effective in improving exercise capacity and quality of life for patients with pulmonary arterial hypertension.
Supporting Evidence
- Exercise training has shown benefits in other respiratory and cardiovascular diseases.
- Only three studies have previously examined exercise training in pulmonary arterial hypertension.
- Improvements in exercise capacity and quality of life have been reported without adverse events.
Takeaway
This study is testing if exercise can help people with a serious lung condition feel better and be more active.
Methodology
This is a prospective, single blind, randomised controlled trial with 34 subjects undergoing a 12 week supervised exercise program followed by a home exercise program.
Potential Biases
Potential bias may arise from the self-reported nature of exercise adherence and outcomes.
Limitations
The study may not generalize to all patients with pulmonary arterial hypertension due to specific inclusion and exclusion criteria.
Participant Demographics
Participants will be adults diagnosed with idiopathic or familial pulmonary arterial hypertension, in WHO functional class II or III.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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