FlowTriever System for Treating Pulmonary Embolism
Author Information
Author(s): Hart Einar A., Eenhoorn Paul, Nijkeuter Mathilde, Ruigrok Dieuwertje, van der Heijden Joris J., Voskuil Michiel, Liu Tommy K. K., Balder Jan Willem, van de Hoef Tim P., van der Harst Pim, Kraaijeveld Adriaan O., Dickinson Michael G.
Primary Institution: University Medical Centre Utrecht
Hypothesis
Can the FlowTriever thrombosuction system serve as a safe alternative to systemic thrombolysis in high-risk pulmonary embolism patients?
Conclusion
The FlowTriever thrombosuction system appears to be a minimally invasive alternative treatment for high-risk pulmonary embolism with low complication rates.
Supporting Evidence
- The technical success rate of the FlowTriever system was 100%.
- 30-day all-cause mortality was 29%.
- Major bleeding occurred in 24% of patients, with one event related to the FlowTriever procedure.
- A significant reduction in mean pulmonary arterial pressure was observed.
- Reduction in right ventricular end-diastolic dimension was also noted.
Takeaway
Doctors used a special device called FlowTriever to help patients with serious blood clots in their lungs, and it worked really well without causing many problems.
Methodology
This was a single-centre retrospective cohort study analyzing data from patients treated with the FlowTriever system from December 2021 to March 2024.
Potential Biases
The study included patients with high-risk factors and those who had contraindications for standard treatment, which may introduce bias.
Limitations
The study had a modest sample size, single-arm design, and variability in available data, which may affect the conclusions.
Participant Demographics
The cohort included 21 patients, with 14 classified as high risk and 7 as intermediate-high risk, including a significant number presenting with circulatory arrest.
Statistical Information
P-Value
0.012
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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