Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) in association with an adenocarcinoma: a case report
2008

Case Report of DIPNECH with Adenocarcinoma

Sample size: 1 publication Evidence: low

Author Information

Author(s): Warth Arne, Herpel Esther, Schmähl Astrid, Storz Konstantina, Schnabel Philipp A

Primary Institution: Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany

Hypothesis

Is DIPNECH a precursor lesion for pulmonary carcinoid tumors?

Conclusion

This case contributes to a better understanding of DIPNECH and its associated pathologies.

Supporting Evidence

  • DIPNECH is considered a precursor for pulmonary carcinoid tumors.
  • Only 40 cases of DIPNECH have been reported in the literature.
  • This case is the first report of DIPNECH associated with a pulmonary adenocarcinoma.

Takeaway

DIPNECH is a rare lung condition that can be linked to other tumors, like adenocarcinoma. This case shows how they can occur together.

Methodology

The patient underwent a diagnostic thoracotomy with sleeve lobectomy and systematic lymphadenectomy.

Potential Biases

Potential bias due to the rarity of the condition and limited existing literature.

Limitations

Only one case is reported, limiting generalizability.

Participant Demographics

60-year-old female patient with a 10 pack-year smoking history.

Digital Object Identifier (DOI)

10.1186/1752-1947-2-21

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