Propolis Prevents Hepatorenal Injury Induced by Chronic Exposure to Carbon Tetrachloride
2012

Propolis Protects Against Liver and Kidney Damage from Carbon Tetrachloride

Sample size: 24 publication 10 minutes Evidence: moderate

Author Information

Author(s): Monika Bhadauria

Primary Institution: School of Studies in Zoology, Jiwaji University, Gwalior, India

Hypothesis

Propolis extract has a protective role against hepatorenal injury induced by carbon tetrachloride.

Conclusion

Propolis extract effectively prevents liver and kidney damage caused by chronic exposure to carbon tetrachloride.

Supporting Evidence

  • Propolis therapy significantly reduced the leakage of liver enzymes in circulation.
  • Propolis extract restored levels of blood sugar and hemoglobin towards control.
  • Histopathological examinations showed improved liver and kidney architecture with propolis treatment.

Takeaway

Propolis, a natural substance made by bees, helps protect the liver and kidneys from damage caused by a harmful chemical.

Methodology

Female Sprague Dawley rats were exposed to carbon tetrachloride for 12 weeks and then treated with propolis extract for 2 weeks.

Limitations

The study was conducted on rats, and results may not directly translate to humans.

Participant Demographics

24 female Sprague Dawley rats, average weight 130 ± 10 g.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1155/2012/235358

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