Organic Papers
2011
Crystal Structure of a Podophyllotoxin Derivative
publication
Evidence: moderate
Author Information
Author(s): Li Yan, Wang Huo, Chen Hong, Chen Li-Ting, Liu Jing
Primary Institution: The Pharmacy Department of the General Hospital of the Chinese People’s Armed Police Force
Hypothesis
The study aims to present the crystal structure of a new podophyllotoxin derivative.
Conclusion
The crystal structure of the compound shows normal bond lengths and angles, consistent with related compounds.
Supporting Evidence
- The compound's structure was determined using X-ray crystallography.
- The bond lengths and angles were found to be normal and consistent with related compounds.
- Weak intermolecular hydrogen bonds stabilize the crystal packing.
Takeaway
Scientists created a new version of a medicine that helps fight cancer and looked at its structure to see how it is built.
Methodology
The compound was synthesized in two steps and analyzed using X-ray crystallography.
Digital Object Identifier (DOI)
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