Glyphosate-based herbicide metabolic profiles in human urine samples through proton nuclear magnetic resonance analysis
2024

Glyphosate Metabolism in Humans

Sample size: 8 publication Evidence: moderate

Author Information

Author(s): Tajai Preechaya, Konguthaithip Giatgong, Chaikhaeng Thanyaphisit, Jaikang Churdsak

Primary Institution: Chiang Mai University

Hypothesis

Does glyphosate undergo metabolism in humans?

Conclusion

The study provides evidence suggesting that glyphosate may be metabolized in humans, with various metabolites detected in urine samples.

Supporting Evidence

  • Glyphosate and its metabolites were detected in urine samples.
  • The study found a moderate correlation between glyphosate concentration and its metabolites.
  • 1H-NMR analysis was used to identify the metabolites present in urine.
  • Participants were herbicide sprayers with documented exposure to glyphosate.

Takeaway

This study looked at how glyphosate, a common herbicide, is processed in the human body by checking urine samples from workers who use it.

Methodology

The study analyzed urine samples from horticultural workers using proton nuclear magnetic resonance (1H-NMR) to identify glyphosate and its metabolites.

Limitations

The study had a small sample size and focused only on a specific group of workers.

Participant Demographics

All participants were male, aged between 24 and 60 years, with an average age of 43 years.

Digital Object Identifier (DOI)

10.5599/admet.2476

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