Evidence of space–time clustering of childhood acute lymphoblastic leukaemia in Sweden
1999
Childhood Acute Lymphoblastic Leukaemia Clustering in Sweden
Sample size: 645
publication
Evidence: moderate
Author Information
Author(s): Gustafsson B, Carstensen J
Primary Institution: Karolinska Institute
Hypothesis
Is there space-time clustering of childhood acute lymphoblastic leukaemia in Sweden?
Conclusion
There is a significant clustering of childhood acute lymphoblastic leukaemia cases in Sweden among children aged 5 to 15 years.
Supporting Evidence
- The study examined 645 cases of childhood acute lymphoblastic leukaemia.
- There was a significant excess of case pairs close in date and place of birth.
Takeaway
The study looked at kids with a type of blood cancer in Sweden and found that some of them were born close together in time and place.
Methodology
The close-pair method of Knox was used to analyze recorded cases of childhood acute lymphatic leukaemia.
Participant Demographics
Children diagnosed with acute lymphoblastic leukaemia in Sweden from 1973 to 1989.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website