Wound Healing Effects of Oncidium flexuosum Extract and Microcurrent
Author Information
Author(s): Fernanda Oliveira de G. de Gaspi, Mary Ann Foglio, João Ernesto de Carvalho, Gláucia Maria T. Santos, Milene Testa, José Roberto Jr. Passarini, Cristiano Pedroso de Moraes, Marcelo A. Marreto Esquisatto, Josué S. Mendonça, Fernanda A. Sampaio Mendonça
Primary Institution: Centro Universitário Hermínio Ometto (UNIARARAS)
Hypothesis
The study evaluates the wound healing activity of hydroalcoholic leaf extract of Oncidium flexuosum combined with microcurrent stimulation.
Conclusion
The combination of Oncidium flexuosum extract and microcurrent stimulation significantly accelerates wound healing compared to other treatments.
Supporting Evidence
- The extract of Oncidium flexuosum contains active compounds that speed up the healing process.
- Microcurrent stimulation significantly increased the number of fibroblasts and blood vessels in the wound area.
- The combination treatment resulted in complete reepithelization of the wound by day 10.
Takeaway
This study found that a plant extract and a small electric current can help heal wounds faster in rats.
Methodology
Wistar rats were divided into four groups and treated with different combinations of Oncidium flexuosum extract and microcurrent, with wound healing assessed through structural and morphometric analysis.
Limitations
The study was conducted on a small sample size of rats, which may limit the generalizability of the results.
Participant Demographics
Male Wistar rats, weighing 250–300 g.
Statistical Information
P-Value
<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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