Aptamer runner: An accessible aptamer structure prediction and structural prediction algorithm for visualization of selected aptamers
2024
A New Tool for Sorting and Visualizing Aptamers
Commentary
Author Information
Author(s): John J. Rossi
Primary Institution: Center for RNA Biology and Therapeutics Beckman Research Institute of the City of Hope
Conclusion
Aptamer Runner is a new bioinformatic tool that simplifies the sorting and visualization of aptamers from large sequence pools.
Supporting Evidence
- Aptamer Runner combines features of existing algorithms to improve aptamer analysis.
- The tool visualizes clusters of sequence and structural similarities.
- Several investigators have verified the utility of Aptamer Runner.
Takeaway
Aptamer Runner helps scientists pick the best aptamers, which are tiny molecules that can stick to other things, making their work easier.
Methodology
The study describes a new method using computer-based experiential learning to sort aptamer sequences from next-gen sequencing data.
Digital Object Identifier (DOI)
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