Enhancing Older Adult Participation in MoTrPAC Trial
Author Information
Author(s): Espinoza Sara, Coen Paul, Talton Jennifer, Houmard Joseph, Moreau Kerrie, Nicklas Barbara
Primary Institution: Cedars-Sinai Medical Center
Hypothesis
Older adults are often underrepresented in clinical research, and targeted recruitment strategies can improve their inclusion.
Conclusion
Adjusting eligibility criteria and employing targeted recruitment strategies can significantly enhance the representation of older adults in clinical trials.
Supporting Evidence
- Older adults made up only 20.6% of the randomized participants as of March 1, 2024.
- Only 4.5% of screened older adults were randomized compared to higher rates in younger age groups.
- The largest reason for exclusion of older adults was the use of lipid-lowering medication.
Takeaway
This study is about getting more older people to join exercise research by changing rules and using better ways to invite them.
Methodology
The study randomized approximately 1980 sedentary, healthy participants to a 12-week exercise intervention, monitoring recruitment and adjusting criteria to enhance older adult representation.
Potential Biases
Potential bias in participant selection due to age-related eligibility criteria.
Limitations
Older adults were significantly underrepresented at the start of recruitment due to strict eligibility criteria.
Participant Demographics
Participants were categorized into three age groups: 18-39, 40-59, and 60+ years.
Digital Object Identifier (DOI)
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