Dose verification of helical tomotherapy intensity modulated radiation therapy planning using 2D-array ion chambers
2010

Dose Verification in Helical Tomotherapy Using 2D-Array Ion Chambers

Sample size: 10 publication 10 minutes Evidence: high

Author Information

Author(s): Xu S, Xie C, Ju Z, Dai X, Gong H, Wang L, Yang J

Primary Institution: Department of Radiation Oncology, PLA General Hospital, Beijing, China

Hypothesis

To investigate the clinical usage of dose verification of Helical Tomotherapy plans by using 2D-array ion chambers.

Conclusion

The MatriXX with Multicube is a reliable system for measuring both absolute and relative dose distributions in helical Tomotherapy IMRT planning.

Supporting Evidence

  • The dose distributions measured by the MatriXX 2D array were in good agreement with plans calculated by the Tomotherapy planning system.
  • The discrepancy between the measured dose and predicted dose was within ±3%.
  • The mean passing rates of 2 mm dose grid with γ-parameter ≤1 were 97.37% and 96.91% in coronal and sagittal directions, respectively.

Takeaway

This study shows that a special device can help doctors check if the right amount of radiation is given to patients during treatment.

Methodology

The study used a pixel-segmented ionisation chamber device and a Multicube phantom to measure dose distributions from ten selected Tomotherapy IMRT/IGRT head and neck plans.

Potential Biases

Potential biases may arise from the calibration and setup of the MatriXX device.

Limitations

The effective field-size of the MatriXX system limits its use for large IMRT fields.

Participant Demographics

Participants were ten patients with nasopharyngeal carcinoma.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.2349/biij.6.2.e24

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