LONG-TERM IMPACTS OF A LIFESTYLE INTERVENTION IN OLDER ADULTS WITH DIABETES AND OVERWEIGHT OR OBESITY: LOOK AHEAD
2024

Long-Term Impacts of a Lifestyle Intervention in Older Adults with Diabetes and Overweight or Obesity

Sample size: 5145 publication Evidence: moderate

Author Information

Author(s): Huckfeldt Peter, Semelka Charles, Jakicic John

Hypothesis

The long-term benefits of a lifestyle intervention for weight loss in older adults with diabetes and obesity have not been rigorously established.

Conclusion

The intensive lifestyle intervention improved diabetes control and related health outcomes but did not significantly reduce cardiovascular events compared to the control group.

Supporting Evidence

  • The ILI group had greater initial improvements in cardiovascular disease risk factors compared to DSE.
  • ILI positively impacted diabetes control and complications.
  • ILI improved depression and physical health-related quality of life.
  • The study transitioned to an observational study to assess long-term benefits.

Takeaway

This study looked at how a weight loss program helped older people with diabetes, showing it helped with diabetes management but not heart problems.

Methodology

The study was a randomized controlled trial comparing an intensive lifestyle intervention with a control condition over up to 11 years.

Limitations

The study did not find significant differences in cardiovascular outcomes between the intervention and control groups.

Participant Demographics

Individuals aged 45-76 years with type 2 diabetes and overweight/obesity.

Digital Object Identifier (DOI)

10.1093/geroni/igae098.0385

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