Metathesis access to monocyclic iminocyclitol-based therapeutic agents
2011
Metathesis Access to Monocyclic Iminocyclitol-Based Therapeutic Agents
publication
Evidence: high
Author Information
Author(s): Dragutan Ileana, Dragutan Valerian, Mitan Carmen, Vosloo Hermanus CM, Delaude Lionel, Demonceau Albert, Grela Karol
Primary Institution: Institute of Organic Chemistry, Romanian Academy
Conclusion
The review highlights the role of olefin metathesis in the synthesis of iminocyclitols, emphasizing its advantages over traditional methods.
Supporting Evidence
- The review emphasizes the importance of metathesis reactions in synthesizing therapeutic agents.
- Recent developments in azasugars are highlighted as significant for drug development.
- Metathesis offers shorter and more efficient synthetic routes compared to traditional methods.
Takeaway
This study shows how a special chemical reaction called metathesis helps create important medicines from sugar-like compounds.
Methodology
The review discusses various synthetic strategies using olefin metathesis for the preparation of iminocyclitols.
Digital Object Identifier (DOI)
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