Sub-Typing of Rheumatic Diseases Based on a Systems Diagnosis Questionnaire
2011

Sub-Typing of Rheumatic Diseases Using a Questionnaire

Sample size: 49 publication Evidence: moderate

Author Information

Author(s): Herman A. van Wietmarschen, Theo H. Reijmers, Anita J. van der Kooij, Jan Schroën, Heng Wei, Thomas Hankemeier, Jacqueline J. Meulman, Jan van der Greef

Primary Institution: Leiden University

Hypothesis

Can a systems diagnosis questionnaire effectively identify symptom patterns in patients with rheumatic diseases?

Conclusion

The systems diagnosis questionnaire can successfully identify relevant symptom groups for sub-typing patients with rheumatic diseases.

Supporting Evidence

  • The questionnaire included symptoms from both Chinese and Western medicine.
  • Categorical principal component analysis revealed significant dimensions related to disease stages.
  • Cold and Heat symptom patterns were identified as relevant for treatment optimization.

Takeaway

Doctors can use a special questionnaire to better understand the symptoms of patients with joint pain, helping them find the right treatment.

Methodology

49 patients completed a systems diagnosis questionnaire with 106 questions, and categorical principal component analysis was used to analyze the data.

Limitations

The study is limited by the reliance on patient-reported symptoms and may benefit from expert observations.

Participant Demographics

Patients with various rheumatic diseases, including rheumatoid arthritis, osteoarthritis, and fibromyalgia.

Digital Object Identifier (DOI)

10.1371/journal.pone.0024846

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