Antioxidant and free radical scavenging activity of Spondias pinnata
2008
Antioxidant Properties of Spondias pinnata
Sample size: 6
publication
Evidence: moderate
Author Information
Author(s): Bibhabasu Hazra, Santanu Biswas, Nripendranath Mandal
Primary Institution: Bose Institute
Hypothesis
The study aims to evaluate the in vitro antioxidant activities of Spondias pinnata stem bark extract.
Conclusion
The study provides evidence that a 70% methanol extract of Spondias pinnata stem bark is a potential source of natural antioxidants.
Supporting Evidence
- The extract showed total antioxidant activity with a TEAC value of 0.78 ± 0.02.
- The IC50 values for scavenging of hydroxyl, superoxide, and nitric oxide were 112.18 ± 3.27 μg/ml, 13.46 ± 0.66 μg/ml, and 24.48 ± 2.31 μg/ml, respectively.
- The extract was found to be a potent iron chelator with IC50 = 66.54 ± 0.84 μg/ml.
- The total phenolic content was 91.47 ± 0.004 mg/ml gallic acid equivalent.
- The total flavonoid content was 350.5 ± 0.004 mg/ml quercetin equivalent.
Takeaway
This study found that a plant called Spondias pinnata can help fight bad things in our body called free radicals, which can make us sick.
Methodology
The study used a 70% methanol extract of Spondias pinnata stem bark to test its antioxidant activities in vitro.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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