Advanced gastric cancer showing long-term complete remission in response to S-1 monotherapy: two case reports
2008

Long-term Remission in Advanced Gastric Cancer with S-1 Treatment

Sample size: 2 publication Evidence: low

Author Information

Author(s): Mitomi Hiroyuki, Kishimoto Ichiro, Amemiya Akifumi, Kaneda Goro, Adachi Ken, Shimoda Takuya, Takigawa Masakazu, Fukui Naoshi, Ohkura Yasuo

Primary Institution: National Hospital Organization Sagamihara Hospital

Hypothesis

Can S-1 monotherapy lead to long-term complete remission in patients with advanced gastric cancer?

Conclusion

The study reports two cases of advanced gastric cancer achieving long-term complete remission after S-1 monotherapy.

Supporting Evidence

  • Case 1 showed complete remission after S-1 treatment and surgery.
  • Case 2 maintained complete remission for 39 months after S-1 treatment.

Takeaway

Two patients with advanced stomach cancer got better and stayed healthy for a long time after taking a special medicine called S-1.

Methodology

The patients received S-1 monotherapy, followed by surgery and further S-1 treatment.

Limitations

The study is based on only two case reports, limiting generalizability.

Participant Demographics

One male aged 65 and one female aged 59.

Digital Object Identifier (DOI)

10.1186/1757-1626-1-405

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