The taming of an impossible child: a standardized all-in approach to the phylogeny of Hymenoptera using public database sequences
2011

A New Bioinformatics Pipeline for Analyzing Hymenoptera Phylogeny

Sample size: 120000 publication Evidence: moderate

Author Information

Author(s): Peters Ralph S, Meyer Benjamin, Krogmann Lars, Borner Janus, Meusemann Karen, Schütte Kai, Niehuis Oliver, Misof Bernhard

Primary Institution: Zoologisches Forschungsmuseum Alexander Koenig

Hypothesis

Can a novel bioinformatics pipeline effectively analyze the phylogeny of Hymenoptera using public database sequences?

Conclusion

The bioinformatics pipeline developed allows for efficient phylogenetic analysis of Hymenoptera, revealing persistent problems in the tree and suggesting future research directions.

Supporting Evidence

  • The pipeline processed over 120,000 sequences to analyze Hymenoptera phylogeny.
  • Tree reconstruction revealed that 'Symphyta' is paraphyletic.
  • Data coverage in the final dataset was only 1.55%.

Takeaway

The researchers created a new tool to help scientists study the family tree of insects like bees and wasps using lots of data from the internet.

Methodology

A bioinformatics pipeline was developed for downloading, formatting, filtering, and analyzing public sequence data from GenBank.

Limitations

Data coverage is low, and many relationships within Hymenoptera remain unresolved.

Digital Object Identifier (DOI)

10.1186/1741-7007-9-55

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