Detecting Fenthion in Human Serum
Author Information
Author(s): Kasiotis Konstantinos M., Souki Helen, Tsakirakis Angelos N., Carageorgiou Haris, Theotokatos Spiridon A., Haroutounian Serkos A., Machera Kyriaki
Primary Institution: Benaki Phytopathological Institute
Hypothesis
A simple and effective analytical procedure can be developed for the determination of fenthion residues in human serum samples.
Conclusion
The headspace SPME technique is efficient for determining fenthion and identifying its metabolites in human serum samples.
Supporting Evidence
- The method requires only 1 mL of serum and avoids tedious pre-treatment steps.
- Fenthion was detected at levels as low as 1.51 ng/mL in serum.
- Recoveries of fenthion ranged from 79 to 104% across different concentration levels.
- Two metabolites of fenthion were identified using the developed method.
Takeaway
Scientists found a quick and easy way to check for a pesticide called fenthion in people's blood, which helps understand its effects.
Methodology
The method involved headspace solid-phase microextraction combined with gas chromatography-mass spectrometry.
Limitations
The study did not assess long-term exposure effects or include a diverse demographic of participants.
Participant Demographics
Participants were 25 experienced pesticide applicators from olive groves in Greece.
Digital Object Identifier (DOI)
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