Six‐degrees‐of‐freedom pelvic bone monitoring on 2D kV intrafraction images to enable multi‐target tracking for locally advanced prostate cancer
2025

Monitoring Pelvic Bone Movement During Prostate Cancer Treatment

Sample size: 20 publication Evidence: high

Author Information

Author(s): Emily A Hewson, Owen Dillon, Per R Poulsen, Jeremy T Booth, Paul J Keall

Primary Institution: The University of Sydney

Hypothesis

Can real-time pelvic bone motion monitoring improve treatment accuracy for prostate cancer patients?

Conclusion

The study successfully demonstrated accurate pelvic bone motion monitoring, which can enhance real-time treatment adaptation for prostate cancer.

Supporting Evidence

  • The method achieved sub-mm and sub-degree accuracy in monitoring pelvic bone motion.
  • 66% of images showed relative displacements between the prostate and pelvic bones exceeding 2 mm.
  • The study utilized data from the TROG 15.01 Stereotactic Prostate Ablative Radiotherapy trial.

Takeaway

Doctors can now track how the pelvic bones move during prostate cancer treatment, helping them aim the radiation better.

Methodology

The study developed a method to monitor pelvic bone motion using 2D kV images from 20 patients treated in a clinical trial, applying template matching for motion tracking.

Limitations

The method's accuracy may be limited by the range of pelvic rotations considered and the need for patient-specific DRR libraries.

Participant Demographics

Patients with locally advanced prostate cancer treated in the TROG 15.01 trial.

Digital Object Identifier (DOI)

10.1002/mp.17465

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