Periodontal treatment effects on endothelial function and cardiovascular disease biomarkers in subjects with chronic periodontitis: protocol for a randomized clinical trial
2011

Effects of Periodontal Treatment on Heart Health

Sample size: 98 publication 10 minutes Evidence: moderate

Author Information

Author(s): Jorge H Ramírez, Roger M Arce, Adolfo Contreras

Primary Institution: Universidad del Valle

Hypothesis

Periodontal treatment with scaling and root planning supplemented with chlorhexidine improves endothelial function and other biomarkers of cardiovascular disease in subjects with moderate to severe periodontitis.

Conclusion

The study aims to determine if periodontal treatment can improve heart health markers in patients with chronic periodontitis.

Supporting Evidence

  • Periodontal disease is linked to systemic diseases like atherosclerosis.
  • Improvement in cardiovascular markers has been observed after periodontal treatment.
  • Randomized controlled trials are needed to confirm the effects of periodontal treatment on heart health.

Takeaway

This study is trying to find out if cleaning teeth and gums can help make hearts healthier.

Methodology

This is a randomized, single-blind clinical trial comparing two periodontal treatment strategies in 98 subjects with moderate to severe periodontitis.

Potential Biases

Potential biases may arise from the single-blind design and the specific selection of participants.

Limitations

The study may not be generalizable to all populations due to the specific inclusion criteria and the focus on severe periodontitis.

Participant Demographics

Participants are adults aged 25 and older with moderate to severe periodontitis.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI 1.14-1.36

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1745-6215-12-46

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