Molecular Epidemiology of Dengue Virus Strains from Finnish Travelers
Author Information
Author(s): Huhtamo Eili, Uzcátegui Nathalie Y., Siikamäki Heli, Saarinen Auli, Piiparinen Heli, Vaheri Antti, Vapalahti Olli
Primary Institution: Haartman Institute, University of Helsinki, Finland
Conclusion
The study characterized 11 dengue virus strains isolated from Finnish travelers and provided new information about strains circulating in India, Sri Lanka, and Ghana.
Supporting Evidence
- The study analyzed 11 dengue virus isolates from Finnish travelers.
- All four dengue virus serotypes were represented among the isolates.
- Phylogenetic analysis showed clustering of isolates consistent with patients' travel history.
Takeaway
Researchers studied dengue viruses from Finnish travelers to learn more about where these viruses come from and how they spread.
Methodology
The study involved isolating dengue virus strains from serum samples of patients returning from dengue-endemic areas and analyzing them using monoclonal antibodies and phylogenetic methods.
Limitations
The study did not establish associations between virus serotype or strain and disease severity due to the uneventful outcomes of the patients.
Participant Demographics
Finnish travelers returning from dengue-endemic areas between 2000 and 2005.
Digital Object Identifier (DOI)
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