To Pace Or Not To Pace! — Prevention Of Atrial Fibrillation After Coronary Artery Bypass Surgery
2005

Preventing Atrial Fibrillation After Heart Surgery

Sample size: 120 Editorial Evidence: moderate

Author Information

Author(s): Amit Vora

Hypothesis

Can biatrial pacing effectively prevent atrial fibrillation after coronary artery bypass surgery?

Conclusion

Biatrial pacing is effective in reducing the incidence of atrial fibrillation after CABG surgery and shortens hospital stay.

Supporting Evidence

  • Atrial fibrillation occurs in up to 40% of patients after CABG surgery.
  • Biatrial pacing reduced AF incidence to 17.5% compared to 30% with LA pacing and 45% in the control group.
  • Patients receiving both amiodarone and pacing had significantly lower AF rates than those receiving placebo.

Takeaway

This study shows that using two sites for pacing the heart can help stop a common problem after heart surgery called atrial fibrillation, which can make patients stay in the hospital longer.

Methodology

A prospective, randomized, double-blinded, placebo-controlled study comparing biatrial pacing with left atrial pacing and no pacing.

Limitations

The study may not address cost-effectiveness and the role of single-site pacing.

Participant Demographics

Patients undergoing CABG surgery, well matched in age, LV function, and use of beta-blockers.

Statistical Information

P-Value

p=0.02

Statistical Significance

p=0.04

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