Cromolyn Sodium vs Nedocromil Sodium for Exercise-Induced Asthma in Children
Author Information
Author(s): F. M. de Benedictis, G. Tuteri, A. Niccoli, D. Mezzetti, L. Rossi, L. Bruni
Primary Institution: Clinica Pediatrica, Policlinico Monteluce, Universit& di Perugia, Italy
Hypothesis
Is cromolyn sodium (CS) more effective than nedocromil sodium (NS) in preventing exercise-induced asthma (EIA) in children?
Conclusion
Cromolyn sodium and nedocromil sodium provide equal protection against exercise-induced asthma in children.
Supporting Evidence
- Both CS and NS provided significant protection from exercise-induced asthma.
- 62.5% of subjects were completely protected by CS, while 50% were protected by NS.
- Both drugs were significantly better than placebo in preventing EIA.
Takeaway
This study tested two asthma medications to see which one works better for kids when they exercise. Both medicines worked equally well to help prevent asthma attacks.
Methodology
A double-blind, randomized, cross-over, placebo-controlled study was conducted with eight asthmatic children aged 7 to 11 years.
Limitations
The small sample size may limit the generalizability of the findings.
Participant Demographics
Eight asthmatic children (5 males, 3 females) aged 7 to 11 years.
Statistical Information
P-Value
p<0.005
Statistical Significance
p<0.005
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