Antimicrobial Resistance Pattern of Shigella species Over Five Years
Author Information
Author(s): Urvashi Saxena, Sonal Dutta, Renu
Primary Institution: Lady Hardinge Medical College and Associated Hospitals, New Delhi, India
Hypothesis
What is the incidence and prevalence of Shigella serogroups and their drug resistance patterns in a tertiary-care hospital in North India over five years?
Conclusion
The study found a high level of antimicrobial resistance in Shigella species isolated from stool samples over a five-year period.
Supporting Evidence
- Shigella accounts for a significant proportion of bacillary dysentery cases in tropical countries.
- Over 98% of isolates were found to be multiple drug-resistant.
- The most commonly affected age group was children aged 1-5 years.
Takeaway
Doctors studied stool samples from sick patients to see how many had Shigella germs and how resistant they were to medicines. They found many germs that didn't respond to common treatments.
Methodology
This cross-sectional study included patients with acute, bloody diarrhea from 2004 to 2008, analyzing stool samples for Shigella isolation and antimicrobial susceptibility.
Limitations
The study is retrospective and conducted in a single hospital, which may limit the generalizability of the findings.
Participant Demographics
The study included 106 patients, with a mean age of 17.66 years, predominantly affecting children under five years old.
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