Change in antihypertensive drug prescribing after guideline implementation: a controlled before and after study
2011

Impact of Guidelines on Antihypertensive Drug Prescribing

Sample size: 11800 publication Evidence: moderate

Author Information

Author(s): Sipilä Raija, Helin-Salmivaara Arja, Korhonen Maarit Jaana, Ketola Eeva

Primary Institution: Current Care, Finnish Medical Society Duodecim

Hypothesis

The study aimed to assess the impact of a guideline implementation intervention on antihypertensive drug prescribing.

Conclusion

The multifaceted guideline implementation intervention did not lead to significant changes in prescribing performance.

Supporting Evidence

  • The use of multiple concurrent medications increased in all subgroups.
  • Intervention patients with hypertension only had an odds ratio of 1.12 for receiving multiple medications.
  • Control patients had an odds ratio of 1.13 for receiving multiple medications.

Takeaway

Doctors tried to follow new rules for prescribing blood pressure medicine, but it didn't really change how they prescribed it.

Methodology

A controlled before and after study evaluating a multifaceted quality programme in a health centre.

Potential Biases

Self-selection of active GPs may reduce the generalizability of the results.

Limitations

The study may have been underpowered, and the lack of personal feedback on prescribing could have affected the results.

Participant Demographics

The median age of patients was 70 or more, with approximately two-thirds being female.

Statistical Information

P-Value

p = 0.06 for diabetes patients receiving two or more concurrent antihypertensive agents.

Confidence Interval

95% CI 0.99, 1.25 for intervention patients with hypertension only.

Digital Object Identifier (DOI)

10.1186/1471-2296-12-87

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