2-Chloro-N-[(2-methylphenyl)sulfonyl]acetamide
2011
Study of 2-Chloro-N-(2-methylphenylsulfonyl)acetamide
publication
Evidence: moderate
Author Information
Author(s): Shakuntala K., Foro Sabine, Gowda B. Thimme
Primary Institution: Mangalore University
Hypothesis
The study investigates the effects of substituents on the crystal structures of sulfonamide compounds.
Conclusion
The crystal structure of 2-chloro-N-(2-methylphenylsulfonyl)acetamide features specific hydrogen bonding interactions and torsion angles that are consistent with similar compounds.
Supporting Evidence
- The study determined the crystal structure of the compound using X-ray diffraction.
- The compound exhibits both intramolecular and intermolecular hydrogen bonding.
- The torsion angles and dihedral angles were measured and compared to similar compounds.
Takeaway
This study looks at how different parts of a molecule can change its shape and how it sticks together, which is important for understanding certain drugs.
Methodology
The compound was synthesized and characterized using X-ray diffraction and infrared spectroscopy.
Digital Object Identifier (DOI)
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