Post-traumatic stress disorder in paediatric cancer survivors and their families
Author Information
Author(s): Low Chen Ee, Tan Sheryl Yen Pin, Loh Andre, Yu Jingrong, Ong Joel Zuo Er, Loh Caitlin Yuen Ling, Yau Chun En, Lee Ainsley Ryan Yan Bin, Ho Cyrus Su Hui
Primary Institution: Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Hypothesis
What is the overall risk of PTSD and severity of PTSS in paediatric cancer survivors and their family nucleus?
Conclusion
Paediatric cancer survivors have an increased risk of PTSD and lower severity of PTSS compared to non-cancer controls.
Supporting Evidence
- Paediatric cancer survivors have a risk ratio of 2.36 for developing PTSD compared to non-cancer controls.
- Female survivors and those older at diagnosis have a significantly higher risk of PTSD.
- Family nucleus did not show a significantly increased risk of PTSD.
- Lower education, income, and social status are risk factors for PTSD and PTSS.
Takeaway
Kids who survive cancer might feel really sad or scared about what happened to them, and it's important to help them and their families feel better.
Methodology
Systematic review and meta-analysis of studies comparing PTSD and PTSS in paediatric cancer survivors and their families with non-cancer controls.
Potential Biases
Potential publication bias identified.
Limitations
Heterogeneity across studies and variability in assessment tools for PTSD and PTSS.
Participant Demographics
Included 10,812 paediatric cancer survivors and their families, with a mix of genders and ages.
Statistical Information
P-Value
p<0.05
Confidence Interval
95% CI 1.37–4.06 for PTSD risk ratio; 95% CI −0.50 to −0.08 for PTSS severity.
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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