Trends in Nasopharyngeal Carcinoma and Extranodal NK/T-cell Lymphoma Incidence in Taiwan
Author Information
Author(s): Yeh Shyh-An, Chiu Liang-Chun, Lin Hsin-Chieh, Li Hung-Ju, Lin Sheng-Fung, Su Yu-Chieh
Primary Institution: National Kaohsiung University of Science and Technology, Kaohsiung, Taiwan
Hypothesis
The study aimed to evaluate the trends in the incidence of ENKTL and NPC in Taiwan within the last 15–30 years.
Conclusion
The incidence rates of nasopharyngeal carcinoma and extranodal NK/T-cell lymphoma in Taiwan have significantly decreased over the past two decades.
Supporting Evidence
- The annual age-adjusted incidence rates of ENKTL and NPC decreased significantly.
- The incidence rates of NPC in various age groups showed a downward trend.
- EBV seroprevalence in Taiwan remained stable from 1984 to 2007.
Takeaway
This study looked at how many people got two types of cancer in Taiwan over the years, and it found that fewer people are getting these cancers now.
Methodology
An epidemiological study was performed using population-based registry data from the Taiwan Cancer Registry.
Limitations
The trend in the incidence of ENKTL was assessed only from 2008 to 2021 due to data availability, and the EBV seroprevalence data were from studies conducted before the research periods.
Participant Demographics
The study included 39,412 patients diagnosed with NPC, with 75.1% being men, and 872 patients diagnosed with ENKTL, with 64.9% being men.
Statistical Information
P-Value
p = 0.014
Confidence Interval
95% CI: −1.47 to −0.86
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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