Prevalence of Hepatitis B Virus Subgenotypes in Pakistan
Author Information
Author(s): Baig Saeeda, Siddiqui Anwar, Chakravarty Runu, Moatter Tariq
Primary Institution: Ziauddin Medical College, Ziauddin University, Karachi, Pakistan
Hypothesis
What are the prevalent subgenotypes of Hepatitis B virus in Pakistan?
Conclusion
The study confirms that genotype D, particularly subgenotypes D1 and D3, is the most prevalent in Pakistani patients.
Supporting Evidence
- Genotype D was found in 70% of the patients.
- Subgenotypes D1 and D3 were identified among the samples.
- The study highlights the genetic link between HBV strains in Pakistan and neighboring countries.
Takeaway
This study found that most people with Hepatitis B in Pakistan have a specific type of the virus called genotype D.
Methodology
Blood samples were collected from patients diagnosed with HBV, and DNA was extracted and analyzed using PCR and phylogenetic methods.
Limitations
The study may not represent all regions of Pakistan as it was conducted in Karachi.
Participant Demographics
Patients were from various ethnic groups residing in Karachi, Pakistan.
Digital Object Identifier (DOI)
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