HIV infection of non-dividing cells: a divisive problem
2006
HIV Infection of Non-Dividing Cells: A Complex Problem
publication
Evidence: high
Author Information
Author(s): Ariberto Fassati
Primary Institution: University College London
Hypothesis
Understanding how lentiviruses can infect terminally differentiated, non-dividing cells is crucial for HIV-1 transmission and AIDS pathogenesis.
Conclusion
Lentiviruses, such as HIV-1, can efficiently infect non-dividing cells, which is essential for their spread and disease progression.
Supporting Evidence
- Lentiviruses like HIV-1 can infect non-dividing cells, which is crucial for their spread.
- Different retroviruses have varying efficiencies in infecting non-cycling cells.
- HIV-1 can infect cells that are not actively dividing, which is important for its transmission.
Takeaway
HIV can get into cells that aren't dividing, which is important for how the virus spreads and causes disease.
Digital Object Identifier (DOI)
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