The relationship between serum zinc level and preeclampsia
2010

Serum Zinc Levels and Preeclampsia

Sample size: 96 publication Evidence: moderate

Author Information

Author(s): Bahadoran Parvin, Zendehdel Manoush, Movahedian Ahmad, Zahraee Roshanak Hasan

Primary Institution: Isfahan University of Medical Sciences

Hypothesis

Is there a relationship between serum zinc levels and the incidence of preeclampsia in pregnant women?

Conclusion

The study found that serum zinc levels do not have clinical value for managing preeclampsia, but there is a relationship between zinc concentration and the severity of the condition.

Supporting Evidence

  • 62.5% of women in the normal pregnancy group had serum zinc levels under 50 mg/dl.
  • 79.2% of women in the preeclamptic group had serum zinc levels under 50 mg/dl.
  • The mean serum zinc concentration was 47.83 mg/dl for normal pregnancies and 43.66 mg/dl for preeclamptic pregnancies.
  • There was no significant difference in serum zinc levels between the two groups.
  • An association was found between serum zinc concentration and the severity of preeclampsia.

Takeaway

This study looked at whether zinc levels in pregnant women are linked to a serious condition called preeclampsia. It found that while zinc levels were lower in women with preeclampsia, it didn't help doctors manage the condition.

Methodology

A case-control study comparing serum zinc levels in 48 normal pregnancies and 48 preeclamptic pregnancies.

Limitations

The study's small sample size and the potential for geographical and nutritional differences may affect the results.

Participant Demographics

Most participants were aged 20-30 years, with a majority having no history of childbirth.

Statistical Information

P-Value

p = 0.04

Statistical Significance

p = 0.04

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