Adverse Childhood Experiences and Alzheimer’s Disease/Dementia Risk Factors Among Transgender Adults
2024

Adverse Childhood Experiences and Alzheimer's Risk in Transgender Adults

Sample size: 206 publication Evidence: moderate

Author Information

Author(s): Cicero Ethan, Chiow Jobina, Flatt Jason

Primary Institution: Emory University

Hypothesis

The relationship between adverse childhood experiences (ACEs) and Alzheimer's disease risk factors among transgender adults has not been explored.

Conclusion

Transgender adults with adverse childhood experiences are at a higher risk for depression and cognitive decline.

Supporting Evidence

  • Transgender adults report a higher prevalence of adverse childhood experiences.
  • Obesity, hypertension, high cholesterol, and depression were the most prevalent risk factors among the sample.
  • Experiencing any ACE was associated with depression and subjective cognitive decline.

Takeaway

If transgender adults have bad experiences when they are kids, they might get sad or forgetful when they grow up.

Methodology

The study used 2019-2021 Behavioral Risk Factor Surveillance System data to analyze the association between ACEs and ADRD risk factors among TNGE adults.

Participant Demographics

Transgender, nonbinary, and other gender expansive adults aged 45 and older.

Statistical Information

P-Value

p<0.0001

Confidence Interval

95%CI:1.7-5.9

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.1093/geroni/igae098.2484

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