Relapsing Polychondritis Presenting With Hoarseness and Multisystem Involvement: A Diagnostic and Therapeutic Challenge
2024

Relapsing Polychondritis Case Study

Sample size: 1 publication Evidence: low

Author Information

Author(s): Muacevic Alexander, Adler John R, De Silva Shamilka, De Silva Monika, De Silva Pradeep K

Primary Institution: National Hospital of Sri Lanka, Colombo, LKA

Hypothesis

Can relapsing polychondritis be diagnosed and treated effectively in a patient presenting with hoarseness and multisystem involvement?

Conclusion

The case highlights the importance of considering relapsing polychondritis in patients with hoarseness and multisystem involvement, leading to effective treatment.

Supporting Evidence

  • Relapsing polychondritis is a rare autoimmune disorder affecting cartilaginous tissues.
  • The patient presented with hoarseness, inflammatory arthritis, and nasal and ear involvement.
  • Treatment resulted in significant improvement in symptoms and inflammatory markers.
  • The diagnosis was based on clinical evaluation and Modified McAdam criteria.

Takeaway

A 68-year-old woman had a rare disease called relapsing polychondritis that made her voice hoarse and caused pain in her joints and nose, but doctors helped her feel better with medicine.

Methodology

The diagnosis was made using Modified McAdam criteria, and treatment involved intravenous cyclophosphamide and oral prednisolone.

Limitations

The rarity of relapsing polychondritis limits the availability of randomized controlled trials and evidence-based guidelines.

Participant Demographics

68-year-old female, Sri Lankan origin.

Digital Object Identifier (DOI)

10.7759/cureus.74874

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