Management of Hepatic Encephalopathy
Author Information
Author(s): G. Wright, A. Chattree, R. Jalan
Primary Institution: University College London Institute of Hepatology
Hypothesis
There is a need for newer therapies for patients with advanced hepatic encephalopathy and worsening acute liver injury.
Conclusion
Ammonia-lowering therapy remains at the cornerstone of standard medical care for hepatic encephalopathy.
Supporting Evidence
- Reduction of plasma ammonia is the central therapeutic strategy for hepatic encephalopathy.
- High-protein diets are well tolerated in cirrhotic patients.
- Probiotics may help reduce intestinal ammonia production.
Takeaway
Hepatic encephalopathy is a brain condition caused by liver problems, and doctors are looking for better ways to treat it, especially for severe cases.
Methodology
The article reviews current evidence supporting various therapeutic interventions for managing chronic and acute hepatic encephalopathy.
Limitations
There is a lack of conclusive evidence from clinical studies for current best practices.
Digital Object Identifier (DOI)
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