Development and validation of a French patient-based health-related quality of life instrument in kidney transplant: the ReTransQoL
2008

Development of a French Quality of Life Questionnaire for Kidney Transplant Recipients

Sample size: 225 publication Evidence: moderate

Author Information

Author(s): Stéphanie Gentile, Elisabeth Jouve, Bertrand Dussol, Valerie Moal, Yvon Berland, Roland Sambuc

Primary Institution: University of Aix-Marseille II

Hypothesis

The study aims to develop and validate a self-administered quality of life questionnaire for renal transplant recipients in French.

Conclusion

The ReTransQol appears to be a reliable and valid questionnaire for assessing quality of life in kidney transplant recipients.

Supporting Evidence

  • Item generation involved 24 interviews with renal transplant recipients.
  • 225 randomized RTR were sent the first version of the questionnaire.
  • 130 RTR were involved in the validation phase, confirming the questionnaire's construct validity.

Takeaway

Researchers created a new questionnaire to help kidney transplant patients share how they feel about their health and life, and it works well.

Methodology

The study involved three phases: item generation through interviews, item reduction based on response rates and factor analysis, and validation of the questionnaire's psychometric properties.

Potential Biases

Potential bias may arise from the self-reported nature of the questionnaire and the exclusion of non-French speaking patients.

Limitations

The study's sensitivity to change was limited due to a low number of subjects with changes in health status during the study period.

Participant Demographics

Participants were renal transplant recipients aged over 18, with a mean age of approximately 50 years, and included both males and females.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1477-7525-6-78

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