Hypotension in Severe Dimethoate Self-Poisoning
Author Information
Author(s): James Davies, Darren Roberts, Peter Eyer, Nick Buckley, Michael Eddleston
Primary Institution: Guy’s and St Thomas’ Hospital, London, UK
Hypothesis
What are the clinical features and outcomes of severe dimethoate self-poisoning?
Conclusion
Severe dimethoate self-poisoning leads to significant hypotension and shock, resulting in death despite standard treatments.
Supporting Evidence
- Over 40% of patients dying from dimethoate poisoning present with a systolic blood pressure of less than 80 mmHg.
- All three patients died within 2.5 to 32 hours post-admission despite treatment.
- Continuous cardiac monitoring showed no primary cardiotoxic effect of dimethoate.
Takeaway
If someone drinks a dangerous pesticide called dimethoate, it can make their blood pressure drop really low, and they might not get better even with medicine.
Methodology
Case reports of three patients with severe dimethoate poisoning were analyzed, focusing on their clinical presentation and treatment outcomes.
Potential Biases
Potential bias due to the under-resourced setting and lack of comprehensive data collection.
Limitations
The study is limited by the small sample size and lack of resources for advanced monitoring in the treating hospitals.
Participant Demographics
All three patients were adult males aged between 50 and 55 years.
Digital Object Identifier (DOI)
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