Efficacy of PermaNet® 2.0 and PermaNet® 3.0 against insecticide-resistant Anopheles gambiae in experimental huts in Côte d'Ivoire
2011

Effectiveness of PermaNet® 2.0 and 3.0 Against Resistant Mosquitoes

Sample size: 7291 publication Evidence: high

Author Information

Author(s): Koudou Benjamin G, Koffi Alphonsine A, Malone David, Hemingway Janet

Primary Institution: Département Environnement et Santé, Centre Suisse de Recherches Scientifiques, Côte d'Ivoire

Hypothesis

The study aims to evaluate the efficacy and wash resistance of PermaNet® 3.0 compared to PermaNet® 2.0 against insecticide-resistant Anopheles gambiae.

Conclusion

Unwashed PermaNet® 3.0 caused significantly higher mortality against pyrethroid-resistant Anopheles gambiae and Culex spp than PermaNet® 2.0 and the conventionally treated net.

Supporting Evidence

  • Mortality rates of over 80% were recorded only with unwashed PermaNet® 3.0.
  • Significantly more An. gambiae s.s and Culex spp were caught in control huts than with other treatments.
  • The proportion of mosquitoes exiting the huts was significantly lower with the control than for the treatment arms.

Takeaway

The new PermaNet® 3.0 mosquito net works better than the older version against resistant mosquitoes, especially when it's not washed.

Methodology

The study compared the efficacy of washed and unwashed PermaNet® 2.0 and 3.0 against resistant mosquitoes in experimental huts over 12 weeks.

Limitations

The study did not measure blood feeding rates as a standard parameter due to ethical reasons.

Participant Demographics

Five adult male volunteers slept in the huts each night during the study.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/1475-2875-10-172

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