Electroencephalography (EEG) for Neurological Prognostication in Post-Anoxic Coma Following Cardiac Arrest and Its Relationship to Outcome
2024

EEG Patterns and Outcomes in Post-Anoxic Coma After Cardiac Arrest

Sample size: 81 publication 10 minutes Evidence: moderate

Author Information

Author(s): Shivji Zaitoon, Bendahan Nathaniel, McInnis Carter, Woodford Timothy, Einspenner Michael, Calder Lisa, Boissé Lomax Lysa, Shukla Garima, Winston Gavin P.

Primary Institution: Kingston Health Science Center

Hypothesis

What is the relationship between EEG patterns and outcomes in patients with post-anoxic coma following cardiac arrest?

Conclusion

Highly malignant EEG patterns, seizures, and myoclonus are linked to poor outcomes, while EEG reactivity and improvement on follow-up EEG are associated with better outcomes.

Supporting Evidence

  • 22% of patients had a favourable outcome.
  • None of the patients with highly malignant EEG survived.
  • 94% of patients with myoclonus had unfavourable outcomes.
  • 72% of patients with reactive EEG survived.
  • 67% of patients who showed improvement on follow-up EEG had a favourable outcome.

Takeaway

Doctors looked at brain waves from patients who had a heart stop to see how well they might recover. They found that certain brain wave patterns mean a patient is less likely to get better.

Methodology

This retrospective study reviewed EEG patterns and clinical features of 81 adult patients admitted to the ICU after cardiac arrest from 2017 to 2020.

Potential Biases

Potential bias due to the retrospective nature of the study and reliance on clinical records.

Limitations

The study is limited to a single center and focuses solely on EEG findings without incorporating other prognostic markers.

Participant Demographics

57 males and 24 females, aged 18 to 87 years.

Statistical Information

P-Value

p < 0.001

Statistical Significance

p < 0.001

Digital Object Identifier (DOI)

10.3390/brainsci14121264

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication