A Review of Diffusion Magnetic Resonance Imaging Applications in Skeletal Muscle
Author Information
Author(s): David B. Berry, Joseph A. Gordon III, Vincent Adair, Lawrence R. Frank, Samuel R. Ward
Primary Institution: University of California San Diego
Conclusion
Diffusion magnetic resonance imaging (dMRI) is a promising noninvasive technique for studying skeletal muscle microstructure and architecture, but its clinical adoption is limited due to a lack of understanding of its sensitivity to important biomarkers.
Supporting Evidence
- dMRI allows for noninvasive assessment of muscle microstructure and architecture.
- Understanding muscle microstructure can help predict muscle function.
- dMRI techniques can be applied to study muscle changes due to disease, aging, and injury.
- Current clinical adoption of dMRI is hindered by a lack of understanding of its sensitivity to biomarkers.
Takeaway
This study talks about how scientists can use a special type of MRI to look at muscles without taking samples, which helps understand how muscles work and change with age or injury.
Methodology
The review covers the fundamentals of muscle physiology, dMRI acquisition techniques, modeling, and applications of dMRI in studying skeletal muscle.
Limitations
The clinical application of dMRI is limited by a lack of understanding regarding its sensitivity to clinically important biomarkers.
Digital Object Identifier (DOI)
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