Preterm delivery and risk of breast cancer
1999

Preterm Delivery and Breast Cancer Risk

Sample size: 474156 publication Evidence: moderate

Author Information

Author(s): Melbye M, Wohlfahrt J, Andersen A-M N, Westergaard T, Andersen P K

Primary Institution: Danish Epidemiology Science Centre, Statens Serum Institut

Hypothesis

Does a preterm delivery carry a higher risk of breast cancer than a full-term delivery?

Conclusion

A preterm delivery of 32+ weeks gestation did not significantly increase a woman's risk of contracting breast cancer, but deliveries of less than 32 weeks did show an increased risk.

Supporting Evidence

  • The study included 474,156 women to assess breast cancer risk.
  • Preterm deliveries of less than 32 weeks gestation were associated with a 1.72-fold increased risk of breast cancer.
  • Relative risks for different gestational ages were calculated after adjusting for various factors.

Takeaway

Having a baby too early might not be bad for breast cancer risk unless it's really early, like before 32 weeks.

Methodology

The study used a population-based cohort of women and linked various registries to identify breast cancer cases.

Participant Demographics

Women born since April 1935 in Denmark.

Statistical Information

Confidence Interval

1.00–4.45

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1038/sj.bjc.6690399

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