Impact of Hospital Birth Volume on Neonate Outcomes After Hypothermia
Author Information
Author(s): Craig Alexa, Cutler Anya, Kerecman Jay, Melendi Misty, Seften Leah Marie, Ryzewski Matthew, Zanno Allison, Barkhuff Whittney, O'Reilly Deirdre
Hypothesis
Outborn neonates from smaller birth volume hospitals would have more frequent adverse short-term outcomes following therapeutic hypothermia.
Conclusion
Neonates born in small volume hospitals had significantly higher odds of death or severe gray matter injury following therapeutic hypothermia.
Supporting Evidence
- 531 neonates were included from small, medium, and large volume hospitals.
- The odds of the combined outcome were 4.3-fold higher in small versus large birth volume hospitals.
- TH was initiated at a median of 4.5, 4, and 2 hours of life respectively for small, medium, and large hospitals.
Takeaway
Babies born in smaller hospitals are more likely to have serious problems after treatment than those born in larger hospitals.
Methodology
Multicenter retrospective study comparing outcomes for small, medium, and large hospitals using multivariable logistic regression.
Participant Demographics
Included neonates from small (<500 births/year), medium (501-1500 births/year), and large (>1500 births/year) hospitals.
Statistical Information
P-Value
0.004
Confidence Interval
95% CI = 1.6, 12.1
Statistical Significance
p=0.004
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website