Testicular infarction secondary to protein S deficiency: a case report
2006

Testicular Infarction Due to Protein S Deficiency: A Case Report

Sample size: 1 publication Evidence: low

Author Information

Author(s): Damian McKay, Conor Marron, Robin Brown

Primary Institution: The Department of Surgery, Daisy Hill Hospital, Newry, Co Down, N. Ireland, UK

Hypothesis

Is testicular infarction a potential complication of protein S deficiency?

Conclusion

The case highlights a rare but potential complication of protein S deficiency and demonstrates the importance of adequate anticoagulation in these patients.

Supporting Evidence

  • Protein S deficiency is a rare blood disorder that can lead to thrombophilia.
  • Testicular infarction is a rare complication of thrombophilia.
  • The patient's INR was sub-therapeutic at 1.4 despite anticoagulation therapy.
  • Ultrasound confirmed absent blood flow to the left testis.
  • Histological examination revealed a necrotic testis with evidence of thrombus.

Takeaway

A man had a part of his testicle die because his blood wasn't flowing properly due to a rare condition. It's important for people with this condition to take their medicine correctly.

Methodology

The patient was examined, underwent ultrasound, and had an orchidectomy to remove the necrotic testis.

Limitations

Only one case is reported, limiting generalizability.

Participant Demographics

A 63-year-old man with a history of protein S deficiency.

Digital Object Identifier (DOI)

10.1186/1471-2490-6-17

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